For Desktops: Mouse will rule over other pointing devices

I don't think any pointing device  touchscreen or motion sensors could surpass the simplicity and ease of computer mouse. Using a mouse requires minimal movement of hands and fingers, you can rest you palm even while you move your mouse. So over a prolonged use, mouse should be more comfortable. The options like touchscreen and motion sensors will never replace the mouse for desktops, touchscreens are definitely better for hand-held devices but when it comes to desktop nothing beats the simple mouse.

(ps: Mouse technology has also evolved over time , ball --> optical --> laser technology.)